US President Joe Biden has voiced his support for a ceasefire after eight days of violence between Israel and Palestinian militants in Gaza.
Mr Biden told Israeli Prime Minister Benjamin Netanyahu that the US was working with Egypt and other countries on halting hostilities.
But the US again blocked a UN Security Council statement calling for a cessation of violence.
The conflict is now in its second week, with little sign of ending.
At least 212 people, including 61 children, have died in Gaza, and 10, including two children, in Israel.
Israel says most of those killed in Gaza are militants and that any civilian deaths are unintentional.
But Hamas, the militant group that runs the territory, disputes this.
According to a White House statement, Mr Biden “encouraged Israel to make every effort to ensure the protection of innocent civilians”.
“The two leaders discussed progress in Israel’s military operations against Hamas and other terrorist groups in Gaza,” it added.
President Biden “expressed his support for a ceasefire and discussed US engagement with Egypt and other partners towards that end”, it said.
The violence has prompted increasing concern internationally.
World leaders and humanitarian organisations have called for measures to prevent the deaths of residents and the chaos wrought by the destruction of buildings and infrastructure.
The US has – for the third time – blocked efforts at the UN Security Council to issue a statement calling on Israel to stop its military offensive, stressing instead its own diplomatic efforts.
“Our calculation at this point is that having those conversations behind the scenes … is the most constructive approach we can take,” White House spokeswoman Jen Psaki told reporters.
Biden follows familiar pattern
Joe Biden is a traditional pro-Israel Democrat. That’s different from Donald Trump who actually changed US policy to adopt Israel’s positions in its conflict with the Arabs. Biden has quietly begun to reverse some, although not all, of that.
But when it comes to air wars with Palestinian militants, he is following a familiar pattern. All US administrations strongly support Israel’s right to defend itself against rocket fire.
Analysts say in the initial phase they generally refrain from public criticism of Israeli air strikes, including at the United Nations, apparently allowing a window of time for Israel to take out militant leaders and infrastructure. However, if the conflict goes on and civilian deaths mount, sometimes they become more critical and start pressing Israel to wind down its military campaign.
In this case Hamas’ firepower has been more sustained and intense than before. But President Biden has now publicly expressed support for a ceasefire in his call with the Israeli Prime Minister Benjamin Netanyahu, and discussed with him “progress in Israel’s military operations against Hamas.”
So perhaps this is the beginning of new phase.
The United Nations has also expressed concerns about the damage to infrastructure in the already impoverished Gaza Strip, home to two million people. It said that 40 schools and four hospitals had been “completely or partially destroyed” in recent days. It also warned that fuel supplies there were running out, threatening basic services.
The World Health Organization’s emergencies chief, Dr Mike Ryan, said all attacks on healthcare needed to stop immediately.
The outbreak of violence began after weeks of rising Israeli-Palestinian tension in occupied East Jerusalem that culminated in clashes at a holy site revered by both Muslims and Jews. Hamas, which controls Gaza, began firing rockets after warning Israel to withdraw from the site, triggering retaliatory air strikes.
What is the latest on the ground?
Israel continued to pummel Gaza with air strikes overnight after Palestinian militants launched rockets at Israeli cities on Monday. Israeli leaders have also, again, vowed to keep up their campaign.
The armed wing of Hamas promised more rockets in return.
Sirens sounded again on Monday night in Israel, with rockets entering in the south and north, close to the Lebanese border.
The Israeli army said it launched artillery towards Lebanon on Monday in response to rocket fire that failed to hit the Jewish state.
Israel Defence Forces (IDF) said it thwarted 160 “terrorist operatives” overnight and destroyed 15 kilometres of Hamas tunnels in Gaza Strip.
At least seven Palestinians were killed in Israeli strikes on Gaza on Monday by the evening.
Mohammad Abu Rayya, a paediatrician in Gaza, told the BBC of the devastation on the ground there.
“We don’t have a morgue here big enough for the killed and the dead bodies,” he said.
“The situation in Gaza is becoming worse and worse, the system is being collapsed and stretched because also we are complaining and suffering from the (lack of) fuel,” he added.
“We need at least 10 years more to build what has been damaged here in Gaza,” he said.
The only coronavirus-testing laboratory in Gaza was knocked out on Monday. The rate of positive Covid-19 tests in Gaza has been 28% – one of the highest in the world.
An Israeli tech executive and father of three, Eitan Singer, told the BBC: “It is not easy – seven days in a row when we go to sleep and almost every evening, every night, we get the kids out of bed, run to shelters. We have 30 seconds to 60 seconds to find a shelter.”
Israel said more than 3,000 rockets had been fired into the country over the past week, calling it an unprecedented number.
The country’s Iron Dome defence system is said to have intercepted 90% of the rockets.
Israeli emergency services have reported an overall total of 311 injuries, six of them severe.
One person has also died of wounds sustained during riots in Israel. Clashes between Arab Israelis and Jewish citizens have left an additional 193 people injured, 10 seriously.
Timeline: How the violence escalated
The worst violence in years between Israel and the Palestinian territory of the Gaza Strip has seen dozens killed. It follows a month of spiralling tensions before open conflict broke out. Here is what happened in the lead-up to the fighting.
Clashes erupt in East Jerusalem between Palestinians and Israeli police.
Palestinians are angry over barriers which had been placed outside the Damascus Gate entrance to the Jerusalem‘s Old City preventing them from gathering there after prayers at the Old City’s al-Aqsa Mosque on what is the first night of the Islamic holy month of Ramadan.
Palestinian discontent had been stoked earlier in the day when President Mahmoud Abbas called off planned elections, implicitly blaming Israel over voting arrangements for Palestinians in East Jerusalem.
Hamas – Mr Abbas’ Islamist rivals who control Gaza and were running in the elections – react angrily to the postponement.
Violence around Damascus Gate and elsewhere in East Jerusalem continues nightly.
Rockets are fired from Gaza at Israel, which responds with air strikes after a relative period of calm between Israel and the Palestinian enclave.
Clashes spread to the mixed Arab-Jewish port city of Jaffa, next to Tel Aviv.
In Jerusalem, Jewish youths, angry over a spate of filmed assaults by Palestinians on Orthodox Jews posted on the TikTok video-sharing app, attack Arabs and chant anti-Arab slogans.
Hundreds of ultra-nationalist Jews shouting “Death to Arabs” march towards Damascus Gate in protest at the Arab assaults on Jews. Clashes erupt at the site between Palestinians and police trying to separate the two groups, injuring dozens of people.
Violence between Arabs and Jews spreads to other parts of the city.
Militants fire dozens of rockets at Israel from Gaza, drawing retaliatory air strikes.
President Abbas’ Fatah faction and Hamas condemn the looming threatened eviction of Palestinian families from their homes in the Sheikh Jarrah district of East Jerusalem by Jewish settlers ahead of a planned court hearing. Hamas calls on Arabs to form “human shields of resistance” there.
In the days that follow, police and protesters repeatedly clash at the site as it becomes a focal point for Palestinian anger.
Militants in Gaza begin sending incendiary balloons into Israel over successive days, causing dozens of fires.
Two Palestinian gunmen are shot dead and a third is wounded after opening fire on Israeli security forces in the northern West Bank. Israeli authorities say the group planned to carry out a “major attack” in Israel.
Later on after Friday prayers – the last of Ramadan – major clashes erupt at the al-Aqsa mosque compound, injuring more than 200 people. Israel’s police force says it used “riot dispersal means”, firing rubber bullets and stun grenades after officers came under a hail of stones and bottles.
A second night of violence erupts in East Jerusalem after tens of thousands of worshippers prayed at the al-Aqsa mosque for Laylat al-Qadr, the holiest night of Ramadan.
Police and protesters clash at Damascus Gate, with police using water cannon, rubber bullets and tear gas against crowds of Palestinians, some throwing stones.
More than 120 Palestinians and some 17 police are injured.
Israel’s Supreme Court postpones the hearing on the Sheikh Jarrah case following calls to delay it because of the growing unrest. Tensions remain high though and more clashes take place between Israeli police and Palestinians in Sheikh Jarrah and at Damascus Gate.
Early morning clashes break out between police and Palestinians at the al-Aqsa mosque compound, where crowds throw stones and officers fire stun grenades.
Palestinian anger has been inflamed by an annual Jerusalem Day march planned for later in the day by hundreds of Israeli nationalists to celebrate Israel’s capture of East Jerusalem in 1967.
The march is due to pass through predominantly Arab parts of the Old City in what is seen by Palestinians as a deliberate provocation. It is rerouted at the 11th hour, but the atmosphere remains volatile with more than 300 Palestinians and some 21 police injured in the violence at the holy site.
Hamas issues an ultimatum to Israel to “withdraw its soldiers… from the blessed al-Aqsa mosque and Sheikh Jarrah” by 18:00. When the deadline passes without an Israeli response, rockets are fired towards Jerusalem for the first time in years.
Israeli Prime Minister Benjamin Netanyahu says the group has “crossed a red line” and Israel retaliates with air strikes, killing three Hamas fighters.
A continuing exchange of rocket-fire and air strikes quickly escalates into the fiercest hostilities between the two sides since they fought a war in 2014.